Collagen

Unlocking the Shiny Beauty of Your Skin, Hair and Nails

Unlocking the Shiny Beauty of Your Skin, Hair and Nails

 The Ultimate Guide to Radiant Skin: Unlocking the Power of Premium Ingredients

Collagen, when combined with a curated mix of minerals, vitamins, eggshell membrane, and keratin, offers a holistic approach to beauty enhancement. This potent blend works synergistically to deeply nourish and revitalize the skin from within. The collagen component bolsters skin elasticity, reducing the appearance of fine lines and wrinkles, while the minerals and vitamins fortify skin health, promoting a radiant complexion. The inclusion of eggshell membrane provides a rich source of proteins, aiding in skin's firmness and texture, while keratin, a fundamental component of hair, skin, and nails, reinforces the skin's natural protective barrier, ensuring lasting hydration and resilience. Together, these ingredients create a comprehensive beauty formula, addressing multiple facets of skin health and rejuvenation for a luminous and youthful glow.

 

Beauty Unveiled: Exploring Ingredients That Transform!

In today's fast-paced world, achieving that coveted youthful glow often feels like an uphill battle. Thankfully, scientific advancements have unveiled a plethora of ingredients that promise to rejuvenate our skin from the inside out. Dive into the world of advanced skincare with us, as we explore the transformative benefits of these powerhouse ingredients.

 

Naticol® Collagen Marine: The Fountain of Youth

Skin Elasticity: Did you know marine collagen is a mirror image of the collagen in our skin? A study by Shoulders, M. (2009) published in Annu Rev Biochem. found that marine collagen significantly improves skin elasticity, making it a key ingredient for a firmer complexion.

Hydration: Combat dryness with marine collagen! A study by Iwai, K. (2005) in J Agric Food Chem. highlighted its ability to fortify the skin's moisture barrier, ensuring long-lasting hydration.

 

Peptan® Collagen Bovine: Nature's Rejuvenator

Collagen Production: Peptan® Collagen Bovine is a treasure trove of amino acids. Research by Postlethwaite, A. E., et al. (1978) in Proceedings of the National Academy of Sciences confirmed its role in boosting natural collagen production, paving the way for firmer skin.

Wrinkle Reduction: Say goodbye to fine lines! The same study revealed that bovine collagen significantly diminishes the appearance of wrinkles, making it a must-have in your skincare arsenal.

 

Hydrolyzed Eggshell Membrane: Nature's Multivitamin

Hydrolyzed eggshell membrane is a natural ingredient derived from the membrane found between the eggshell and the egg white of chicken eggs. Through a process called hydrolysis, this membrane is broken down into smaller, more bioavailable components. Rich in proteins like collagen and elastin, as well as other matrix proteins, hydrolyzed eggshell membrane also contains glycosaminoglycans such as chondroitin sulfate and hyaluronic acid. These components are known for their potential benefits in supporting joint health and skin beauty, including promoting elasticity, moisture retention, and overall skin appearance.

Research by Douglas S. Kalman PhD, RD et al. highlighted its efficacy in enhancing hair, skin, and nails.

 

Hydrolyzed Keratin: The Hair-Skin-Nail Trinity

Hydrolyzed keratin is a processed form of keratin, a fibrous structural protein that is a key component of hair, skin, and nails. The process of hydrolyzation involves breaking down the keratin protein into smaller, more manageable fragments, typically through a process that uses water and enzymes.

Elasticity & Firmness: keratin, the building block of hair, skin, and nails, is a game-changer for skin elasticity. A study by George J. Dias et al. (2022) in Food Chemistry emphasized its role in maintaining a youthful appearance.

Moisture Retention: bid adieu to dry skin! Hydrolyzed keratin has a unique ability to lock in moisture, ensuring a plump and hydrated complexion.

 

Hyaluronic Acid (HA): The Hydration Hero

Hyaluronic acid (HA) is a naturally occurring substance found in the human body, primarily in connective tissues, skin, and eyes. It is a glycosaminoglycan, a type of molecule that helps to maintain and regulate water balance in tissues. HA has gained popularity in the skincare and beauty industry for its unique ability to retain moisture, making it a sought-after ingredient in various topical formulations.

Wrinkle Reduction: HA isn't just a buzzword; it's backed by science! A study by Tzu-Fang Hsu et al. (2021) in Nutrients revealed its prowess in reducing wrinkles and improving skin dryness, making it a skincare superstar.

 

Folic Acid: The Cellular Whisperer

Folic acid, also known as folate or vitamin B9, is a water-soluble vitamin that plays a crucial role in various bodily functions, particularly in cell division and DNA synthesis. It is an essential nutrient, which means that the body cannot produce it on its own and must obtain it through dietary sources or supplements.

Cellular Function: folic acid isn't just for expectant mothers; it plays a pivotal role in skin cell growth and turnover. Research by Özge Aşkın MD et al. (2021) in Clinics in Dermatology underscored its significance in achieving a flawless complexion.

 

L-selenmethionine & Zinc Bisglycinate: The Dynamic Duo

The combination of selenium and zinc offers a multifaceted approach to health support, with synergistic benefits that encompass antioxidant protection, immune system support, thyroid health, skin health, wound healing, and reproductive health. Incorporating both selenium and zinc into your diet or supplement regimen can help optimize these essential physiological functions and promote overall health and well-being.

Antioxidant Protection: these minerals are your skin's best defense against oxidative stress. A study by David L. Vollmer et al. (2018) in Int J Mol Sci highlighted their role in enhancing skin health.

 

Vitamin A & E: The Age-Definers

Vitamin A and E are two essential vitamins that have garnered attention for their potential benefits in skincare and anti-aging. Here's a closer look at each:

Vitamin A is a fat-soluble vitamin that exists in various forms, with retinol being the most commonly recognized.

Vitamin E is a group of compounds with antioxidant properties. Alpha-tocopherol is the most active form of vitamin E in the human body.

Why Used for Anti-Age and Beauty:

Combined Benefits: When used together, vitamin A and E can complement each other's benefits. While vitamin A promotes skin renewal and collagen production, vitamin E provides antioxidant protection and hydration.

Holistic Approach: Incorporating vitamins A and E into skincare routines can offer a holistic approach to anti-aging and beauty, addressing multiple aspects like wrinkles, fine lines, uneven skin tone, and overall skin health.

Versatility: These vitamins can be found in various skincare products, from serums and creams to oils and masks, catering to different preferences and skin types.

Cell Turnover & Protection: These vitamins are the unsung heroes of skincare. A review by Dattola, A. et al. (2020) in Curr Nutr Rep explored their pivotal role in skin health and rejuvenation.

 

Magnesium Ascorbate: The Brightening Beacon

Magnesium ascorbate is a compound that combines magnesium with ascorbic acid, which is another name for vitamin C. This combination is used as a dietary supplement to provide both magnesium and vitamin C in a single form.

Here are some key points about magnesium ascorbate:

Buffered Form: Magnesium ascorbate is often considered a buffered form of vitamin C, which means it is less acidic than pure ascorbic acid. This can be beneficial for individuals who have sensitive stomachs or gastrointestinal issues.

Benefits of Magnesium: Magnesium is an essential mineral that plays a crucial role in numerous physiological functions, including muscle and nerve function, bone health, and energy production. It also supports cardiovascular health and helps regulate blood pressure.

Benefits of Vitamin C: Vitamin C is a powerful antioxidant that supports immune function, collagen production, wound healing, and iron absorption. It also helps protect cells from oxidative stress and supports overall skin health.

Combined Benefits: By combining magnesium and vitamin C, magnesium ascorbate offers the potential benefits of both nutrients in a single supplement. This can be particularly convenient for individuals looking to support multiple aspects of their health with fewer supplements.

Brightening & Even Skin Tone: This buffered form of vitamin C is your ticket to a radiant complexion. A study by Ryo Takatori et al. (2015) in Skin Pharmacol Physiol confirmed its efficacy in promoting even skin tone.

 

Experience the Difference with Shiny Beauty Blend™

Elevate your skincare game with Shiny Beauty Blend™. Merging the synergistic benefits of premium collagens, potent antioxidants, and essential nutrients, this blend promises a luminous, youthful, and radiant complexion.

 

Embrace the future of skincare today!

Clinical Studies and latest articles

Naticol® Collagen Marine

Shoulders, M. (2009), Annu Rev Biochem., 78:929-58.

 

Iwai, K. (2005), J Agric Food Chem., 53(16):6531-6.

 

Peptan® Collagen Bovine

Postlethwaite, A. E., et al., 1978. Chemotactic attraction of human fibroblasts to type I, II, and III collagens and collagen-derived peptides. Proceedings of the National Academy of Sciences, 75(2), 871-875. doi:10.1073/pnas.75.2.871

 

Gniadecka, M., 1998. Water and protein structure in photoaged and chronically aged skin. Journal of the European Academy of Dermatology and Venereology, 11. doi:10.1016/s0926-9959(98)95059-0

 

Asserin, J. et al., 2015. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Journal of Cosmetic Dermatology, doi: 10.1111/jocd.12174

 

Guillerminet, F. et al., 2010, Hydrolyzed collagen improves bone metabolism and biomechanical parameters in ovariectomized mice: An in vitro and in vivo study. Bone, 46:827-834

 

Guillerminet, F. et al., 2012, Hydrolyzed collagen improves bone status and prevents bone loss in ovariectomized C3H/HeN mice. Osteoporosis International, 23(7):1909-1919

 

Daneault, A. et al., 2014, Hydrolyzed collagen contributes to osteoblast differentiation in vitro and subsequent bone health in vivo. Osteoarthritis and Cartilage, 22:S131

 

Daneault, A. et al., 2017, Biological effect of hydrolyzed collagen on bone metabolism. Critical Reviews in Food Science and Nutrition, 57(9):1922-1937

 

Hays N.P. et al., 2009, Effects of whey and fortified collagen hydrolysate protein supplements on nitrogen balance and body composition in older women. Journal of the American Dietetic Association, 109:1082-1087.

 

Jiang J.X. et al., 2014, Collagen peptides improve knee osteoarthritis in elderly women: A 6-month randomized, double-blind, placebo-controlled study. Agro FOOD Industry Hi Tech 25: 19-23

 

Dar, Q. et al., 2017. Daily oral consumption of hydrolyzed type 1 collagen is chondroprotective and anti-inflammatory in murine posttraumatic osteoarthritis. PLoS ONE 12(4):e0174705

 

Jiang J.X. et al., 2014, Collagen peptides improve knee osteoarthritis in elderly women: A 6-month randomized, double-blind, placebo-controlled study. Agro FOOD Industry Hi Tech, 25:19-23

 

Hydrolized eggshell membrane

Douglas S. Kalman PhD, RD, CCRC, FACN, Susan Hewlings PhD, RD. The effect of oral hydrolyzed eggshell membrane on the appearance of hair, skin, and nails in healthy middle-aged adults: A randomized double-blind placebo-controlled clinical trial.

https://onlinelibrary.wiley.com/doi/full/10.1111/jocd.13275

 

Yavuz Emre Arslan, et al. 2017. Fabrication of human hair keratin/jellyfish collagen/eggshell-derived hydroxyapatite osteoinductive biocomposite scaffolds for bone tissue engineering: From waste to regenerative medicine products. Colloids and Surfaces B: Biointerfaces. Volume 154, 1 June 2017, Pages 160-170.

https://www.sciencedirect.com/science/article/abs/pii/S0927776517301522

 

Sim, WJ., Ahn, J., Lim, W. et al. Anti-skin aging activity of eggshell membrane administration and its underlying mechanism. Mol. Cell. Toxicol. 19, 165–176 (2023).

https://link.springer.com/article/10.1007/s13273-022-00291-5

 

Yoo J, Park K, Yoo Y, Kim J, Yang H, Shin Y. Effects of Egg Shell Membrane Hydrolysates on Anti-Inflammatory, Anti-Wrinkle, Anti-Microbial Activity and Moisture-Protection. Korean J Food Sci Anim Resour. 2014;34(1):26-32. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597828/

 

Irene Neuhauser, M.D. 1957. Avian Egg-Shell Membrane as a Culture Medium for Dermatophytes

Author Affiliations. AMA Arch Derm. 1957;75(3):401-404.

https://jamanetwork.com/journals/jamadermatology/article-abstract/524942

 

Yoo JH, Kim JK, Yang HJ, Park KM. Effects of Egg Shell Membrane Hydrolysates on UVB-radiation-induced Wrinkle Formation in SKH-1 Hairless Mice. Korean J Food Sci Anim Resour. 2015;35(1):58-70.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682498/

 

Marimuthu Chandramohan. 2020. Application and merits of Eggshell Membrane in Cosmetics. Research Journal of Topical and Cosmetic Sciences. Year : 2020, Volume : 11, Issue : 1. 24- 31.

https://www.indianjournals.com/ijor.aspx?target=ijor:rjtcs&volume=11&issue=1&article=006

 

Hydrolysed Keratin

George J. Dias a, Thilanka N. Haththotuwa a, David S. Rowlands b, Martin Gram b, Alaa El-Din A. Bekhit c. 2022. Wool keratin – A novel dietary protein source: Nutritional value and toxicological assessment. Food Chemistry. Volume 383, 30 July 2022.

https://www.sciencedirect.com/science/article/abs/pii/S0308814622003983

 

Massimo Milani, Francesca Colombo, GFM-O-Trial Investigators Group. 2023. Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair loss (androgenetic alopecia, AGA or FAGA or telogen effluvium). A prospective, randomized, 3-month, controlled, assessor-blinded study. Skin Research and Technology. Volume29, Issue6. June 2023.

https://onlinelibrary.wiley.com/doi/full/10.1111/srt.13381

 

Sandleen Feroz, Nawshad Muhammad, Jithendra Ratnayake, George Dias. 2020. Keratin - Based materials for biomedical applications. Bioactive Materials. Volume 5, Issue 3, September 2020, Pages 496-509.

https://www.sciencedirect.com/science/article/pii/S2452199X20300591

 

Doris Hexsel MD, Vivian Zague PhD, Michael Schunck PhD, Carolina Siega BSc, Fernanda O Camozzato MD, Steffen Oesser PhD. 2017. Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails. Journal of Cosmetic DermatologyVolume 16, Issue 4 p. 520-526.

https://onlinelibrary.wiley.com/doi/abs/10.1111/jocd.12393

 

Miho Miyanaga; Taro Uchiyama; Akira Motoyama; Nobuhiko Ochiai; Osamu Ueda; Masashi Ogo. 2021. Oral Supplementation of Collagen Peptides Improves Skin Hydration by Increasing the Natural Moisturizing Factor Content in the Stratum Corneum: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Skin Pharmacol Physiol (2021) 34 (3): 115–127. https://karger.com/spp/article-abstract/34/3/115/296023/Oral-Supplementation-of-Collagen-Peptides-Improves

 

Ryo Takatori et al. 2015. Effects of Food-Derived Collagen Peptides on the Expression of Keratin and Keratin-Associated Protein Genes in the Mouse Skin. Skin Pharmacol Physiol (2015) 28 (5): 227–235. https://karger.com/spp/article-abstract/28/5/227/295818/Effects-of-Food-Derived-Collagen-Peptides-on-the

 

Hyaluronic Acid

Tzu-Fang Hsu, et al., 2021. Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study. Nutrients. 2021 Jul; 13(7): 2220. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308347/

 

Zoe Diana Draelos, et. al., 2021. Efficacy Evaluation of a Topical Hyaluronic Acid Serum in Facial Photoaging. Dermatol Ther (Heidelb). 2021 Aug; 11(4): 1385–1394.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322246/

 

Richard D. Price, M.G. Berry, Harshad A. Navsaria, 2007. Hyaluronic acid: the scientific and clinical evidence. Journal of Plastic, Reconstructive & Aesthetic Surgery. Volume 60, Issue 10, October 2007, Pages 1110-1119.

https://www.sciencedirect.com/science/article/abs/pii/S1748681507001805

 

Bruna Bravo, et al. 2022. Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence. Dermatologic Therapy Volume 35, Issue 12. https://onlinelibrary.wiley.com/doi/full/10.1111/dth.15903

 

Federica Carlomagno, et al. 2022. Anti-Skin-Aging Effect of a Treatment with a Cosmetic Product and a Food Supplement Based on a New Hyaluronan: A Randomized Clinical Study in Healthy Women. Cosmetics 2022, 9(3), 54

https://www.mdpi.com/2079-9284/9/3/54

 

Qian Sun, et al. 2022. Effectiveness of Dietary Supplement for Skin Moisturizing in Healthy Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Front. Nutr., 02 June 2022. Sec. Clinical Nutrition. Volume 9 – 2022.

https://www.frontiersin.org/articles/10.3389/fnut.2022.895192/full

 

Imke Göllner, et al. 2017. Ingestion of an Oral Hyaluronan Solution Improves Skin Hydration, Wrinkle Reduction, Elasticity, and Skin Roughness: Results of a Clinical Study. The Journal of Evidence-Based Integrative Medicine.

https://journals.sagepub.com/doi/full/10.1177/2156587217743640

 

Folic acid

Özge Aşkın MD a, Tuğba Kevser Üstünbaş Uzunçakmak MD a, Neval Altunkalem MD a, Yalçın Tüzün. 2021. Vitamin deficiencies/hypervitaminosis and the skin. Clinics in Dermatology. Volume 39, Issue 5, September–October 2021, Pages 847-857.

https://www.sciencedirect.com/science/article/abs/pii/S0738081X21000742

 

Almohanna, H.M., Ahmed, A.A., Tsatalis, J.P. et al. The Role of Vitamins and Minerals in Hair Loss: A Review. Dermatol Ther (Heidelb) 9, 51–70 (2019).

https://link.springer.com/article/10.1007/s13555-018-0278-6?fbclid=IwAR12p0kJ_vyhqHZ-gwV4ARAYkEKN8czblSFZ7pIr-h6lvFb14H-K5qEyqZg&swcfpc=1

 

L-selenmethionine

David L. Vollmer, et al. 2018. Enhancing Skin Health: By Oral Administration of Natural Compounds and Minerals with Implications to the Dermal Microbiome. Int J Mol Sci. 2018 Oct; 19(10): 3059.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213755/

 

Graeme Ewan Glass. 2020. Cosmeceuticals: The Principles and Practice of Skin Rejuvenation by Nonprescription Topical Therapy. Aesthetic Surgery Journal Open Forum, Volume 2, Issue 4. https://academic.oup.com/asjopenforum/article/2/4/ojaa038/5891009

 

Corinne Granger, et al. 2019. Prospective Evaluation of the Efficacy of a Food Supplement in Increasing Photoprotection and Improving Selective Markers Related to Skin Photo-Ageing. Dermatology and Therapy. Volume 10, pages 163–178, (2020)

https://link.springer.com/article/10.1007/s13555-019-00345-y

 

Iman Al-Saleh. 2007. Status of Selenium, Vitamin E, and Vitamin A among Saudi Adults: Potential Links with Common Endemic Diseases. Journal of Environmental Pathology, Toxicology and Oncology. Volume 26, Issue 3, 2007, pp. 221-243.

https://www.dl.begellhouse.com/journals/0ff459a57a4c08d0,77cc44344880ef23,3b3b066866c7a884.html

 

Zinc Bisglycinate

Elizabeth F. Rostan md, Holly V. DeBuys md, Doren L. Madey. 2002. Evidence supporting zinc as an important antioxidant for skin 03 October 2002. International Journal of Dermatology.

https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1365-4362.2002.01567.x

 

Simran Dhaliwal, et al. 2020. Effects of Zinc Supplementation on Inflammatory Skin Diseases: A Systematic Review of the Clinical Evidence. American Journal of Clinical Dermatology. Volume 21, pages 21–39, (2020).

https://link.springer.com/article/10.1007/s40257-019-00484-0

 

Vitamin A

Özge Aşkın MD a, Tuğba Kevser Üstünbaş Uzunçakmak MD a, Neval Altunkalem MD a, Yalçın Tüzün. 2021. Vitamin deficiencies/hypervitaminosis and the skin. Clinics in Dermatology. Volume 39, Issue 5, September–October 2021, Pages 847-857.

https://www.sciencedirect.com/science/article/abs/pii/S0738081X21000742

 

Dattola, A., Silvestri, M., Bennardo, L. et al. Role of Vitamins in Skin Health: a Systematic Review. Curr Nutr Rep 9, 226–235 (2020).

https://link.springer.com/article/10.1007/s13668-020-00322-4

Iman Al-Saleh. 2007. Status of Selenium, Vitamin E, and Vitamin A among Saudi Adults: Potential Links with Common Endemic Diseases. Journal of Environmental Pathology, Toxicology and Oncology. Volume 26, Issue 3, 2007, pp. 221-243.

https://www.dl.begellhouse.com/journals/0ff459a57a4c08d0,77cc44344880ef23,3b3b066866c7a884.html

 

Vitamin E

Fiore Casale, MMS, Susie Suh, BA, Katerina Yale, MD, Natasha Atanaskova Mesinkovska, MD, PhD. 2021. Clinical Role of Oral Vitamin C and E Therapy in Skin and Hair Disorders. International Journal of Cosmetics and Dermatology. Viii.44. https://ijcd.sciforce.org/index.php/IJCD/article/view/44

Jens J. Thiele, Swarna Ekanayake-Mudiyanselage. 2007. Vitamin E in human skin: Organ-specific physiology and considerations for its use in dermatology. Molecular Aspects of Medicine. Volume 28, Issues 5–6, October–December 2007, Pages 646-667

https://www.sciencedirect.com/science/article/abs/pii/S009829970700057X

Jens J. Thiele MD, Sherry N. Hsieh PhD, Swarna Ekanayake-Mudiyanselage MD. 2005. Vitamin E: Critical Review of Its Current Use in Cosmetic and Clinical Dermatology. Dermatologic Surgery. Volume31, Issues1. Pages 805-813. https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1524-4725.2005.31724

Pierangelo Torquato, Rita Marinelli, Desirée Bartolini, Francesco Galli. Vitamins Chapter 23 - Vitamin E: nutritional aspects. Molecular Nutrition. 2020, Pages 447-485

https://www.sciencedirect.com/science/article/abs/pii/B9780128119075000191

Iman Al-Saleh. 2007. Status of Selenium, Vitamin E, and Vitamin A among Saudi Adults: Potential Links with Common Endemic Diseases. Journal of Environmental Pathology, Toxicology and Oncology. Volume 26, Issue 3, 2007, pp. 221-243.

https://www.dl.begellhouse.com/journals/0ff459a57a4c08d0,77cc44344880ef23,3b3b066866c7a884.html

 

Magnesium Ascorbate

European Food Safety Authority (EFSA). 2020.  Calcium ascorbate, magnesium ascorbate and zinc ascorbate added for nutritional purposes in food supplements. EFSA Journal. Volume 7, Issue 3 994.

https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2009.994

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